PD-1 Monoclonal Antibody (Nivolumab Biosimilar) in vivo

Referência TA410359

Tamanho : 1mg

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PD-1 Monoclonal Antibody (Nivolumab Biosimilar) in vivo

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SKU
TA410359
anti-Human PD-1 Recombinant Monoclonal Antibody (Nivolumab Biosimilar) in vivo Grade
 
Specifications
Product Data
Clone Name Nivolumab (clone: 5C4.B8)
Application Animal Model, ELISA, FC
Recommended Dilution Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Reactivity Human
Antibody Host Mammalian Cells
Isotype IgG4
Clonality Monoclonal
Immunogen Recombinant human PD-1-Fc protein
Buffer 0.2 μm sterile-filtered, 1 x PBS, pH 7.4
Concentration Lot-dependent
Purity >95% by reducing SDS-PAGE
Exotoxin < 1 EU per 1 mg of the protein by the LAL method (In vivo grade)
Purification Protein A or G purification
Conjugation Unconjugated
Stability 12 months from date of receipt when stored at -20 to -70°C or 1 month from date of receipt when stored at 2 to 8°C
Shipping Blue Ice
Predicted Protein Size ~150 kDa
Gene Name programmed cell death 1
Database Link
Background Nivolumab is a humanized IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for additional stability and reduced variability. Nivolumab Biosimilar uses the same protein sequences as the therapeutic antibody nivolumab.
Synonyms CD279; hPD-1; hPD-l; PD1; SLEB2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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