p53 DINP1 Recombinant Antibody, Biotin Conjugated
Referência bsm-61980R-Biotin-20uL
Tamanho : 20uL
Marca : Bioss
Contactar o distribuidor local :
Telefone : +1 850 650 7790
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61980r-biotin-100ul |
| Product Name | p53 DINP1 Recombinant Antibody, Biotin Conjugated |
| Applications | WB, IHC-P, IHC-F |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human p53 DINP1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 94241 |
| Swiss Prot | Q96A56 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | p53DINP1; SIP; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B. |
| Background | Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |