Octyl-beta-D-glucopyranoside [29836-26-8]

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Referência NB-64-34919-1g

Tamanho : 1g

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Marca : Neo Biotech

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Telefone : +1 850 650 7790

Octyl-beta-D-glucopyranoside (Synonyms: Octyl glucoside, 11β-HSD1-IN-11)

Catalog No. T64321 Copy Product Info

Purity: 99.88%

Octyl-beta-D-glucopyranoside (11β-HSD1-IN-11) is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins.

Octyl-beta-D-glucopyranoside

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Synonyms Octyl glucoside, 11β-HSD1-IN-11

Cas No. 29836-26-8

Batch Information

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Purity:99.88%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Octyl-beta-D-glucopyranoside AI Summary

Octyl-beta-D-glucopyranoside shows notable antiviral activity against BKV Gardner ATCC VR837 in human WI38 cells, indicated by a reduction in viral DNA levels with an EC50 value greater than 100,000 nM. Additionally, the compound exhibits cytotoxic effects on human WI38 cells, with a CC50 value also greater than 100,000 nM. Both antiviral and cytotoxic activities were measured after a 2-hour preincubation period and 7 days post-treatment using real-time PCR assays. Furthermore, Octyl-beta-D-glucopyranoside demonstrates enzymatic activity in the ratio of Kcat to Km for Neisseria meningitidis lgtC, with a Kcat/Km ratio of 1.4 /mM/min. In addition, it inhibits Escherichia coli Heptosyltransferase I by 8.3% at a concentration of 1 mM, as indicated by a reduction in ADP release in an ADP/NADH coupling assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Octyl-beta-D-glucopyranoside (11β-HSD1-IN-11) is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins.
Synonyms	Octyl glucoside, 11β-HSD1-IN-11

Chemical Properties

Molecular Weight	292.37
Formula	C₁₄H₂₈O₆
Cas No.	29836-26-8
Smiles	CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90 mg/mL (307.83 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.29 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4203 mL	17.1016 mL	34.2032 mL	171.0162 mL
5 mM	0.6841 mL	3.4203 mL	6.8406 mL	34.2032 mL
10 mM	0.3420 mL	1.7102 mL	3.4203 mL	17.1016 mL
20 mM	0.1710 mL	0.8551 mL	1.7102 mL	8.5508 mL
50 mM	0.0684 mL	0.3420 mL	0.6841 mL	3.4203 mL
100 mM	0.0342 mL	0.1710 mL	0.3420 mL	1.7102 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.