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Ochratoxin A [303-47-9]

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Referência 10-3562-5mg

Tamanho : 5mg

Marca : Focus Biomolecules

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Ochratoxin A | Mycotoxin

CAS:
 303-47-9
Catalog Number:
 10-3562
Ochratoxin A supplier | CAS 303-47-9 | Focus Biomolecules

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5mg$220.00
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Ochratoxin A (303-47-9) is a mycotoxin that causes widespread contamination in foodstuffs and environments thus causing health risks to humans and animals.1 It has been shown to be carcinogenic2, mutagenic3, neurotoxic4, nephrotoxic5 and immunotoxic1. It increases lipid peroxide levels in cells6 and reduces antioxidant defenses2 leading to oxidative DNA damage3.

References/Citations:

  1. Al-Anati and Petzinger (2006); Immunotoxic activity of ochratoxin A, J. Vet. Pharmacol. Ther., 29 79
  2. Cavin et al. (2007); Reduction in antioxidant defenses may contribute to ochratoxin A toxicity and carcinogenicity, Toxicol. Sci., 96 30
  3. Palma et al. (2007); Ochratoxin A-Induced Mutagenesis in Mammalian Cells Is Consistent with the Production of Oxidative Stress, Chem. Res. Toxicol., 20 1031
  4. Sava et al. (2006); Acute neurotoxic effects of the fungal metabolite ochratoxin A, Neurotoxicology, 27 82
  5. Khoi et al. (2021); Ochratoxin A-Induced Nephrotoxicity: Up-to-Date Evidence, Int. J. Mol. Sci., 22 11237
  6. Petrik et al. (2003); Apoptosis and oxidative stress induced by ochratoxin A in rat kidney, Arch. Toxicol., 77 685
303-47-9, NSC-201422, NSC-221991, NSC201422, NSC221991, Ochratoxin, Ochratoxin A, Ochratoxin A supplier
CAS:
303-47-9
Catalog Number:
10-3562
Activity:
Mycotoxin
Chemical Names:
N-[[(3R)-5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine
Alternate Name:
NSC-201422; NSC-221991
Molecular Weight:
403.82
Molecular Formula:

C20H18ClNO6

Solubility:
Soluble in DMSO (20 mg/ml); Ethanol (50 mg/ml)
Physical Properties:
Off-white solid
Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

Download Safety Data Sheet

Product Data Sheet:

Download Product Data Sheet

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee

Ochratoxin A (303-47-9) is a mycotoxin that causes widespread contamination in foodstuffs and environments thus causing health risks to humans and animals.1 It has been shown to be carcinogenic2, mutagenic3, neurotoxic4, nephrotoxic5 and immunotoxic1. It increases lipid peroxide levels in cells6 and reduces antioxidant defenses2 leading to oxidative DNA damage3.

References/Citations:

  1. Al-Anati and Petzinger (2006); Immunotoxic activity of ochratoxin A, J. Vet. Pharmacol. Ther., 29 79
  2. Cavin et al. (2007); Reduction in antioxidant defenses may contribute to ochratoxin A toxicity and carcinogenicity, Toxicol. Sci., 96 30
  3. Palma et al. (2007); Ochratoxin A-Induced Mutagenesis in Mammalian Cells Is Consistent with the Production of Oxidative Stress, Chem. Res. Toxicol., 20 1031
  4. Sava et al. (2006); Acute neurotoxic effects of the fungal metabolite ochratoxin A, Neurotoxicology, 27 82
  5. Khoi et al. (2021); Ochratoxin A-Induced Nephrotoxicity: Up-to-Date Evidence, Int. J. Mol. Sci., 22 11237
  6. Petrik et al. (2003); Apoptosis and oxidative stress induced by ochratoxin A in rat kidney, Arch. Toxicol., 77 685

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NB-48-0693-1MG
Ochratoxin A [303-47-9]
 1mg