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Nitroxazepine [47439-36-1]

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Referência NB-64-03580-10mg

Tamanho : 10mg

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Telefone : +1 850 650 7790

Marca : Neo Biotech

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Contactar o distribuidor local :

Telefone : +1 850 650 7790

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Nitroxazepine

(Synonyms: CIBA 2330Go) Copy Product Info

Synonyms: CIBA 2330Go

Catalog No. T12232 Copy Product Info

Purity: 99.28%

Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression

Cas No. 47439-36-1

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.28%

Appearance:Solid

Color:Yellow

Product Introduction

Bioactivity

Description	Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
In vitro	In vitro effect of Nitroxazepine , as a modulator alone and in combination with hydroxyurea (HU), on cytotoxicity is studied in 16 cases of human chronic myeloid leukemia (CML).
Synonyms	CIBA 2330Go

Chemical Properties

Molecular Weight	341.36
Formula	C₁₈H₁₉N₃O₄
Cas No.	47439-36-1
Smiles	C(CCN(C)C)N1C=2C(OC=3C(C1=O)=CC(N(=O)=O)=CC3)=CC=CC2
Relative Density.	1.270 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (175.77 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9295 mL	14.6473 mL	29.2946 mL	146.4729 mL
5 mM	0.5859 mL	2.9295 mL	5.8589 mL	29.2946 mL
10 mM	0.2929 mL	1.4647 mL	2.9295 mL	14.6473 mL
20 mM	0.1465 mL	0.7324 mL	1.4647 mL	7.3236 mL
50 mM	0.0586 mL	0.2929 mL	0.5859 mL	2.9295 mL
100 mM	0.0293 mL	0.1465 mL	0.2929 mL	1.4647 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

SLC6A4SERTSerotoninTransporterserotonin-norepinephrine reuptakeSerotonin TransporterNitroxazepineInhibitorinhibit5-HTT

Related Tags: Nitroxazepine chemical structure | Nitroxazepine in vitro | Nitroxazepine formula | Nitroxazepine molecular weight