Mouse Noradrenaline (NE) ELISA KIT
Referência MBS268395-96
Tamanho : 96-Strip-Wells
Marca : MyBiosource
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Noradrenaline (NE) ELISA Kit for Mouse
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS268395Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Mouse NE monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and… More details
Product Overview
Online Datasheet in PDFProduct Name
Noradrenaline (NE), ELISA Kit
Full Product Name
Mouse Noradrenaline (NE) ELISA KIT
Product Gene Name
NE elisa kit
Species Reactivity
Mouse
Assay Type
Sandwich
Detection Range
1000 pg/mL-15.6 pg/mL
Sensitivity
Up to 5 pg/mL
Specificity
No cross-reaction with other factors.
Preparation and Storage
Store all reagents at 2-8 degree C.
Inter-assay Precision
<= 12%
Intra-assay Precision
<= 8%
Molecular Weight
57,370 Da
OMIM
gene 604715
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of NE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for NE purchase
MBS268395 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Noradrenaline (NE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NE. The ELISA analytical biochemical technique of the MBS268395 kit is based on NE antibody-NE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for NE. It may not necessarily be applicable to this product.
NCBI Official Full Name
noradrenaline transporter
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter), member 2
NCBI Official Symbol
SLC6A2
NCBI Official Synonym Symbols
NET; NAT1; NET1; SLC6A5
UniProt Protein Name
Sodium-dependent noradrenaline transporter
UniProt Synonym Protein Names
Norepinephrine transporter; NET; Solute carrier family 6 member 2
UniProt Gene Name
SLC6A2
UniProt Synonym Gene Names
NAT1; NET1; SLC6A5; NET
UniProt Entry Name
SC6A2_HUMAN
NCBI Protein Information
sodium-dependent noradrenaline transporter; norepinephrine transporter; neurotransmitter transporter; solute carrier family 6 member 5; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
NCBI Summary for NE
This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Show more UniProt Comments for NE
SLC6A2: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. Defects in SLC6A2 are a cause of orthostatic intolerance (OI). OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter
Chromosomal Location of Human Ortholog: 16q12.2
Cellular Component: neuron projection; cell surface; membrane; integral to plasma membrane; plasma membrane; lipid raft
Molecular Function: protein binding; monoamine transmembrane transporter activity; beta-tubulin binding; alpha-tubulin binding; norephinephrine:sodium symporter activity
Biological Process: response to drug; synaptic transmission; norepinephrine transport; neurotransmitter transport; transport; monoamine transport; response to pain; transmembrane transport
Disease: Orthostatic Intolerance
Show more Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter
Chromosomal Location of Human Ortholog: 16q12.2
Cellular Component: neuron projection; cell surface; membrane; integral to plasma membrane; plasma membrane; lipid raft
Molecular Function: protein binding; monoamine transmembrane transporter activity; beta-tubulin binding; alpha-tubulin binding; norephinephrine:sodium symporter activity
Biological Process: response to drug; synaptic transmission; norepinephrine transport; neurotransmitter transport; transport; monoamine transport; response to pain; transmembrane transport
Disease: Orthostatic Intolerance
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with NE elisa kit
| Reference Product | PubMed Publications |
|---|---|
| SLC18A2 elisa kit | >12 publications with NE and SLC18A2 |
| PICK1 elisa kit | >2 publications with NE and PICK1 |
| STX1A elisa kit | >1 publications with NE and STX1A |
Pathways associated with NE elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Monoamine Transport Pathway antibodies | Monoamine Transport Pathway Diagram |
| Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies | Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram |
| SLC-mediated Transmembrane Transport Pathway antibodies | SLC-mediated Transmembrane Transport Pathway Diagram |
| Transmembrane Transport Of Small Molecules Pathway antibodies | Transmembrane Transport Of Small Molecules Pathway Diagram |
| Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies | Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram |
Diseases associated with NE elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Mental Disorders Antibodies | >120 publications with NE and Mental Disorders |
| Nervous System Diseases Antibodies | >49 publications with NE and Nervous System Diseases |
| Attention Deficit Disorder with Hyperactivity Antibodies | >49 publications with NE and Attention Deficit Disorder with Hyperactivity |
| Cardiovascular Diseases Antibodies | >47 publications with NE and Cardiovascular Diseases |
| Depressive Disorder Antibodies | >36 publications with NE and Depressive Disorder |
| Heart Diseases Antibodies | >32 publications with NE and Heart Diseases |
| Brain Diseases Antibodies | >30 publications with NE and Brain Diseases |
| Hypertension Antibodies | >26 publications with NE and Hypertension |
| Disease Models, Animal Antibodies | >25 publications with NE and Disease Models, Animal |
| Tachycardia Antibodies | >17 publications with NE and Tachycardia |
Organs/Tissues associated with NE elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >276 publications with NE and Brain |
| Nerve Antibodies | >267 publications with NE and Nerve |
| Muscle Antibodies | >44 publications with NE and Muscle |
| Kidney Antibodies | >28 publications with NE and Kidney |
| Placenta Antibodies | >18 publications with NE and Placenta |
| Intestine Antibodies | >2 publications with NE and Intestine |
| Testis Antibodies | >2 publications with NE and Testis |
| Prostate Antibodies | >1 publications with NE and Prostate |
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