Mouse Lipopolysaccharide-binding protein, LBP ELISA Kit
Referência MBS947489-96
Tamanho : 96-Strip-Wells
Marca : MyBiosource
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Telefone : +1 850 650 7790
Lipopolysaccharide Binding (LBP) ELISA Kit for Mouse
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS947489Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LBP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LBP present is bound by the… More details
Product Overview
Online Datasheet in PDFProduct Name
lipopolysaccharide binding protein (LBP), ELISA Kit
Full Product Name
Mouse Lipopolysaccharide-binding protein, LBP ELISA Kit
Product Gene Name
LBP elisa kit
Product Synonym Names
Mouse Lipopolysaccharide-binding protein (LBP) ELISA kit; MGC22233; LPS-binding protein; lipopolysaccharide-binding protein; lipopolysaccharide binding protein
Species Reactivity
Mouse
Assay Type
Quantitative Sandwich
Samples
Serum, plasma, tissue homogenates
Detection Range
12.5 ng/ml-800 ng/ml
Sensitivity
< 3.12 ng/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of mouse LBP. No significant cross-reactivity or interference between mouse LBP and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Molecular Weight
53,055 Da
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of LBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for LBP purchase
MBS947489 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the lipopolysaccharide binding protein (LBP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LBP. The ELISA analytical biochemical technique of the MBS947489 kit is based on LBP antibody-LBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for LBP. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lipopolysaccharide-binding protein
NCBI Official Synonym Full Names
lipopolysaccharide binding protein
NCBI Official Symbol
Lbp
NCBI Official Synonym Symbols
Ly88; Bpifd2
UniProt Protein Name
Lipopolysaccharide-binding protein
Protein Family
Lipopolysaccharide-binding protein
UniProt Gene Name
Lbp
UniProt Synonym Gene Names
LBP
UniProt Entry Name
LBP_MOUSE
NCBI Protein Information
lipopolysaccharide-binding protein
UniProt Comments for LBP
LBP: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular space; cell surface; extracellular region
Molecular Function: lipopolysaccharide binding; lipid binding; receptor binding
Biological Process: positive regulation of tumor necrosis factor biosynthetic process; immune system process; detection of molecule of bacterial origin; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of interleukin-6 production; response to lipopolysaccharide; negative regulation of tumor necrosis factor production; defense response to Gram-negative bacterium; lipid transport; positive regulation of tumor necrosis factor production; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production; positive regulation of interleukin-8 production; lipopolysaccharide transport; defense response to Gram-positive bacterium; transport; defense response to bacterium; macrophage activation during immune response; lipopolysaccharide-mediated signaling pathway; acute-phase response; innate immune response; positive regulation of phagocytosis, engulfment; positive regulation of macrophage activation
Show more Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular space; cell surface; extracellular region
Molecular Function: lipopolysaccharide binding; lipid binding; receptor binding
Biological Process: positive regulation of tumor necrosis factor biosynthetic process; immune system process; detection of molecule of bacterial origin; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of interleukin-6 production; response to lipopolysaccharide; negative regulation of tumor necrosis factor production; defense response to Gram-negative bacterium; lipid transport; positive regulation of tumor necrosis factor production; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production; positive regulation of interleukin-8 production; lipopolysaccharide transport; defense response to Gram-positive bacterium; transport; defense response to bacterium; macrophage activation during immune response; lipopolysaccharide-mediated signaling pathway; acute-phase response; innate immune response; positive regulation of phagocytosis, engulfment; positive regulation of macrophage activation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with LBP elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Innate Immune System Pathway antibodies | Innate Immune System Pathway Diagram |
| LPS Transferred From LBP Carrier To CD14 Pathway antibodies | LPS Transferred From LBP Carrier To CD14 Pathway Diagram |
| NF-kappa B Signaling Pathway antibodies | NF-kappa B Signaling Pathway Diagram |
| Salmonella Infection Pathway antibodies | Salmonella Infection Pathway Diagram |
| Salmonella Infection Pathway antibodies | Salmonella Infection Pathway Diagram |
| Toll Like Receptor 4 (TLR4) Cascade Pathway antibodies | Toll Like Receptor 4 (TLR4) Cascade Pathway Diagram |
| Toll Receptor Cascades Pathway antibodies | Toll Receptor Cascades Pathway Diagram |
| Toll-like Receptor Signaling Pathway antibodies | Toll-like Receptor Signaling Pathway Diagram |
| Toll-like Receptor Signaling Pathway antibodies | Toll-like Receptor Signaling Pathway Diagram |
Diseases associated with LBP elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Pain Antibodies | >2232 publications with LBP and Pain |
| Nervous System Diseases Antibodies | >1899 publications with LBP and Nervous System Diseases |
| Inflammation Antibodies | >265 publications with LBP and Inflammation |
| Necrosis Antibodies | >211 publications with LBP and Necrosis |
| Sepsis Antibodies | >152 publications with LBP and Sepsis |
| Neoplasms Antibodies | >76 publications with LBP and Neoplasms |
| Cardiovascular Diseases Antibodies | >68 publications with LBP and Cardiovascular Diseases |
| Liver Diseases Antibodies | >57 publications with LBP and Liver Diseases |
| Lung Diseases Antibodies | >57 publications with LBP and Lung Diseases |
| Neuralgia Antibodies | >56 publications with LBP and Neuralgia |
Organs/Tissues associated with LBP elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Other Antibodies | >730 publications with LBP and Other |
| Blood Antibodies | >584 publications with LBP and Blood |
| Bone Antibodies | >420 publications with LBP and Bone |
| Joint Antibodies | >176 publications with LBP and Joint |
| Liver Antibodies | >136 publications with LBP and Liver |
| Lung Antibodies | >100 publications with LBP and Lung |
| Brain Antibodies | >61 publications with LBP and Brain |
| Kidney Antibodies | >44 publications with LBP and Kidney |
| Spinal Cord Antibodies | >24 publications with LBP and Spinal Cord |
| Connective Tissue Antibodies | >22 publications with LBP and Connective Tissue |
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