OASB02688 | Mouse Kappa Antibody : Biotin Quimigen Portugal

Goat Anti-Mouse Kappa Antibody - Biotin Conjugated (OASB02688)

Datasheets/Manuals	Printable datasheet for Goat Anti-Mouse Kappa Antibody - Biotin Conjugated (OASB02688)

Product Info
Tested Species Reactivity	Mouse
Predicted Species Reactivity	Mouse
Product Format	Liquid. Phosphate buffered saline containing 0.1% sodium azide
Clonality	Polyclonal
Host	Goat
Conjugation	Biotin
Application	ELISPOT, IHC-P
Additional Information	Description: Pepsin digest of Goat Anti-Mouse Kappa - Pooled antisera from goats hyperimmunized with mouse kappa light chains; purified by affinity chromatography on mouse kappa light chains covalently linked to agarose; reacts with mouse kappa light chains; cross-adsorbed against mouse lambda light chains for minimal reactivity
Reconstitution and Storage	Store at 2-8C
Immunogen	Mouse kappa light chains
Concentration	0.5 mg/mL
Specificity	Kappa

Gene Symbol	IGK
Gene Full Name	immunoglobulin kappa chain complex
Alias Symbols	k, kappa
NCBI Gene Id	243469
Description of Target	Summary:Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the kappa light chain locus from the C57BL/6J inbred mouse strain. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments in this cluster are incapable of encoding a protein and are considered pseudogenes.
Uniprot ID	P01837