MCH TFA (human, mouse, rat) [128315-56-0 (free base)]

Referência M10469-10mg

Tamanho : 10mg

Marca : AbMole Bioscience

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MCH TFA (human, mouse, rat) Structure

Quality Control & Documentation
Biological Activity

MCH TFA (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH TFA (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively.

Chemical Information
Molecular Weight 2500.86
Formula C107H161F3N30O28S4
CAS Number 128315-56-0 (free base)
Solubility (25°C) DMSO 90 mg/mL
Storage -20°C, dry, sealed
References

[1] A W Sailer, et al. Proc Natl Acad Sci U S A. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R