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Synonyms: L-LDH, LDH, LD, LAD, (S)-Lactate: NAD+ oxidoreductase
| Description | Lactate Dehydrogenase, Bovine Heart belongs to the oxidoreductase family and catalyzes the reversible conversion between lactic acid and pyruvic acid. It is mainly used in life science research, the diagnostic detection of tissue damage, and also serves as an enzymatic marker in relevant experiments and assays. |
| In vitro | Lactate Dehydrogenase, Bovine Heart is released into the blood when cardiomyocytes are damaged by foot-and-mouth disease, and its elevated activity serves as a non-specific diagnostic marker for tissue injury [1]. This enzyme can undergo complex interactions with lipids on the cell membrane, and this binding process is regulated by the cellular microenvironment (pH, ionic strength, metabolite concentration), thereby affecting its intracellular localization and catalytic activity [2]. |
| Synonyms | L-LDH, LDH, LD, LAD, (S)-Lactate: NAD+ oxidoreductase |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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