IL18 Antibody
Referência OACD04619-1ML
Tamanho : 1ml
Marca : Aviva Systems Biology
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Telefone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for IL18 Antibody (OACD04619) |
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| Predicted Species Reactivity | Porcine |
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| Product Format | Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | ICC|IHC|IHC-P|IP|WB |
| Reconstitution and Storage | -20°C|2°C to 8°C |
| Immunogen | Range: Tyr36 - Asn192 |
| Purification | Affinity Purified; Protein A Purified |
| Concentration | 1 mg/ml |
| Preservative | 0.02% NaN3 |
| Specificity | The antibody is a rabbit polyclonal antibody raised against IL18. It has been selected for its ability to recognize IL18 in immunohistochemical staining and western blotting. |
| Formulation | PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
| Application Data | Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5,000 Optimal working dilutions must be determined by end user. |
| Gene Symbol | IL18 |
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| Gene Full Name | interleukin 18 |
| Alias Symbols | IFN-gamma-inducing factor, IL-1 gamma, IL-18, interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), interleukin-1 gamma, interleukin-18. |
| NCBI Gene Id | 397057 |
| Protein Name | Interleukin-18 |
| Description of Target | A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. |
| Uniprot ID | O19073 |
| Protein Accession # | NP_999162.1 |
| Nucleotide Accession # | NM_213997 |
| Molecular Weight | 22 kDa |
