IgD Rabbit pAb
Referência MBS8541076-0,1mL-APC
Tamanho : 0.1mL(APC)
Marca : MyBiosource
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IgD Secondary Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8541076MBS8541076 is a secondary antibody targeting IgD. Also known as IgD Rabbit pAb. Reactive in Human. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
IgD, Secondary Antibody
Full Product Name
IgD Rabbit pAb
Product Gene Name
IgD secondary antibody
Product Synonym Names
Ig delta chain C region; IGHD
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purity/Purification
Affinity Purified
Preparation and Storage
Store at -20 degree C for 1 year.
Applications Tested/Suitable for IgD secondary antibody
Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes for IgD secondary antibody
IHC-P: 1:50-200
ELISA: 1:10000-20000
ELISA: 1:10000-20000
Other Notes
Small volumes of IgD secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for IgD. It may not necessarily be applicable to this product.
NCBI Official Full Name
Ig delta chain C region
UniProt Protein Name
Ig delta chain C region
UniProt Gene Name
IGHD
UniProt Entry Name
IGHD_HUMAN
UniProt Comments for IgD
IGHD: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: plasma membrane; integral to membrane
Molecular Function: antigen binding
Biological Process: immune response
Show more Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: plasma membrane; integral to membrane
Molecular Function: antigen binding
Biological Process: immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with IgD secondary antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway antibodies | Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Signaling By The B Cell Receptor (BCR) Pathway antibodies | Signaling By The B Cell Receptor (BCR) Pathway Diagram |
Organs/Tissues associated with IgD secondary antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >104 publications with IgD and Blood |
| Brain Antibodies | >83 publications with IgD and Brain |
| Bone Antibodies | >41 publications with IgD and Bone |
| Thyroid Antibodies | >12 publications with IgD and Thyroid |
| Connective Tissue Antibodies | >6 publications with IgD and Connective Tissue |
| Skin Antibodies | >5 publications with IgD and Skin |
| Liver Antibodies | >5 publications with IgD and Liver |
| Vascular Antibodies | >4 publications with IgD and Vascular |
| Spleen Antibodies | >4 publications with IgD and Spleen |
| Bone Marrow Antibodies | >4 publications with IgD and Bone Marrow |