Human STAT4 Antibody : APC (Phospho-Tyr693)
Referência OAAQ00169-10tests
Tamanho : 10Tests
Marca : Aviva Systems Biology
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Human STAT4 Antibody : APC (Phospho-Tyr693)
Human STAT4 Antibody : APC (Phospho-Tyr693) (OAAQ00169)
| Datasheets/Manuals | Printable datasheet for OAAQ00169 |
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| Tested Species Reactivity | Human, Mouse |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | Stat4Y693-F6 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | APC: Allophycocyanin |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr693 of human phospho Stat4 |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Tyr693 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | Kaplan MH, Sun Y, Hoey T, and Grusby MJ. (1996) Nature. 382: 174-177. Chang H, Zhang S, Oldham I, Naeger L, Hoey T, and Kaplan MH. (2003) Journal of Biological Chemistry. 278: 32471-32477. |
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| Gene Symbol | STAT4 |
| Gene Full Name | signal transducer and activator of transcription 4 |
| Alias Symbols | SLEB11 |
| NCBI Gene Id | 6775 |
| Protein Name | signal transducer and activator of transcription 4 |
| Description of Target | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. |
| Uniprot ID | Q14765 |
| Protein Accession # | NP_001230764.1 |
| Nucleotide Accession # | NM_001243835.1 |
