Human SCF Protein, His tag (Animal-Free)

Referência MBS9719538-0,005mg

Tamanho : 0.005mg

Marca : MyBiosource

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SCF Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9719538

Stem Cell Factor (SCF) is a 166-amino-acid protein with a monomeric molecular weight of approximately 18.5kDa. SCF is the ligand for the tyrosine kinase receptor c-kit, which regulates other Growth Factorss, such as granulocyte colony-stimulating factor… More details

Product Overview

Online Datasheet in PDF
Product Name
SCF, Active Protein
Full Product Name
Human SCF Protein, His tag (Animal-Free)
Product Gene Name
SCF active protein
Product Synonym Names
DCUA; DFNA69; FPH2; FPHH; KL-1; Kitl; MGF; SF; SHEP7; SLF; KIT ligand
Sequence
MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVAwithp olyhistidi netagatthe C-terminus
Host
E coli
Form/Format
The protein was lyophilized from a 0.2 um filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Purity/Purification
>98% as determined by SDS-PAGE
Preparation and Storage
Lyophilized protein should be stored at -20 degree C for 1 year. Upon reconstitution, store at 2 degree C to 8 degree C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20 degree C or -80 degree C for 3-6 months. Avoid repeated freeze/thaw cycles.
Molecular Weight
273
Chromosome Location
Chromosome: 12; NC_000012.11 (88886570..88974250, complement). Location: 12q22
OMIM
145250
3D Structure
ModBase 3D Structure for P21583
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin
<0.1 EU per 1 ug of the protein by the LAL method.
Activity
Measured by its ability to induce TF-1 cells proliferation. The ED?? for this effect is <5 ng/mL.
Usage Notes
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human SCF Protein, His tag (Animal-Free) using the buffer we provided not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for SCF active protein

Cytokines and proteins; Cytology; Cell Research Tools; Cell Culture

Other Notes

Small volumes of SCF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCF purchase

MBS9719538 is an active protein targeting SCF. Also known as Human SCF Protein, His tag (Animal-Free). Host: E coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SCF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kit ligand isoform b
NCBI Official Synonym Full Names
KIT ligand
NCBI Official Symbol
KITLG
NCBI Official Synonym Symbols
SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7
UniProt Protein Name
Kit ligand
UniProt Synonym Protein Names
Mast cell growth factor; MGF; Stem cell factor; SCF; c-Kit ligand
Protein Family
SCF-associated factor
UniProt Gene Name
KITLG
UniProt Synonym Gene Names
MGF; SCF; MGF; SCF; sKITLG
UniProt Entry Name
SCF_HUMAN
NCBI Protein Information
kit ligand; c-Kit ligand; steel factor; stem cell factor; mast cell growth factor; familial progressive hyperpigmentation 2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SCF active protein

 Reference Product  PubMed Publications
 KIT active protein  >3486 publications with SCF and KIT
 STAT3 active protein  >756 publications with SCF and STAT3
 JAK2 active protein  >242 publications with SCF and JAK2
 EPOR active protein  >96 publications with SCF and EPOR
 GRB2 active protein  >79 publications with SCF and GRB2
 LYN active protein  >48 publications with SCF and LYN
 FER active protein  >6 publications with SCF and FER
 CSF2 active protein  >3 publications with SCF and CSF2
 MATK active protein  >3 publications with SCF and MATK

Pathways associated with SCF active protein

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram

Diseases associated with SCF active protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >3156 publications with SCF and Necrosis
 Cardiovascular Diseases Antibodies  >2992 publications with SCF and Cardiovascular Diseases
 Bone Marrow Diseases Antibodies  >2884 publications with SCF and Bone Marrow Diseases
 Nervous System Diseases Antibodies  >2623 publications with SCF and Nervous System Diseases
 Carcinoma Antibodies  >2095 publications with SCF and Carcinoma
 Inflammation Antibodies  >1624 publications with SCF and Inflammation
 Neoplasms, Germ Cell and Embryonal Antibodies  >1532 publications with SCF and Neoplasms, Germ Cell and Embryonal
 Heart Diseases Antibodies  >1261 publications with SCF and Heart Diseases
 Drug Toxicity Antibodies  >1200 publications with SCF and Drug Toxicity
 Breast Neoplasms Antibodies  >1183 publications with SCF and Breast Neoplasms

Organs/Tissues associated with SCF active protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17247 publications with SCF and Blood
 Bone Antibodies  >15624 publications with SCF and Bone
 Vascular Antibodies  >5442 publications with SCF and Vascular
 Brain Antibodies  >4903 publications with SCF and Brain
 Embryonic Tissue Antibodies  >4589 publications with SCF and Embryonic Tissue
 Muscle Antibodies  >3250 publications with SCF and Muscle
 Nerve Antibodies  >3128 publications with SCF and Nerve
 Liver Antibodies  >2324 publications with SCF and Liver
 Connective Tissue Antibodies  >1690 publications with SCF and Connective Tissue
 Skin Antibodies  >1576 publications with SCF and Skin