Human Lambda Antibody : HRP
Referência OASB01882
Tamanho : 1.0mL
Marca : Aviva Systems Biology
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Goat Anti-Human Lambda Antibody - HRP Conjugated (OASB01882)
| Datasheets/Manuals | Printable datasheet for Goat Anti-Human Lambda Antibody - HRP Conjugated (OASB01882) |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Human |
| Product Format | Liquid. 50% glycerol / 50%PBS, pH 7.4 (no preservative added) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Goat |
| Conjugation | HRP |
| Application | WB |
| Additional Information | Description: Pepsin digest of Goat Anti-Human Lambda - Pooled antisera from goats hyperimmunized with human lambda light chains; purified by affinity chromatography on human lambda light chains covalently linked to agarose; reacts with human lambda light chains; cross-adsorbed against human kappa light chains for minimal reactivity |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Human lambda light chains |
| Concentration | Lot specific |
| Specificity | Lambda |
| Source | Pepsin digest of Goat Anti-Human Lambda |
| Application Info | Since applications vary, you should determine the optimum working dilution of the product that is appropriate for your specific need. |
| Cross Absorption | Human-kappa light chains; may react with lambda light chains from other species |
| Gene Symbol | IGL |
|---|---|
| Alias Symbols | IGL@, IGLC6 |
| NCBI Gene Id | 3535 |
| Protein Name | ig lambda-6 chain C region |
| Description of Target | Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. |