Human CD8C Antibody : APC
Referência OASB02599
Tamanho : 25tests
Marca : Aviva Systems Biology
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Human CD8C Antibody : APC (OASB02599)
| Datasheets/Manuals | Printable datasheet for Human CD8C Antibody : APC (OASB02599) |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Human |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugation | APC |
| Application | FC |
| Additional Information | Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer. It is expressed on the "cytotoxic/suppressor" subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR's in antigen recognition. |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Thymocytes and E-rosetted lymphocytes |
| Concentration | Lot specific |
| Specificity | CD8 |
| Gene Symbol | CD8A |
|---|---|
| Gene Full Name | CD8a molecule |
| Alias Symbols | CD8, p32, Leu2 |
| NCBI Gene Id | 925 |
| Protein Name | T-cell surface glycoprotein CD8 alpha chain |
| Description of Target | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P01732 |
| Protein Accession # | NP_001139345.1 |
| Nucleotide Accession # | NM_001145873.1 |
