Glucocerebrosides (Soy) [497155-61-0]

Biological Activity

Glucosylceramide (GluCer) is a major sphingolipid of plant tissue and, thus, abundant in nature and in dietary food sources. Soybean GluCer was comprised primarily (>98%) of ceramide with 4,8-sphingadiene (d18:2(delta4,delta8)) and alpha- hydroxypalmitic acid (h16:0); the remainder had the same backbone with h18:0, h20:0, h22:0 and h24:0 fatty acids.

Glucosylceramide (Soy) has been used:

in liposome preparation to test it effect on human α-synuclein aggregation;

as a long chain base source to test alkaline hydrolysis;

to test its immune modulatory effect on natural killer T lymphocytes and dendritic cells.

Glucosylceramide (Soy) is suitable:

for intraperitoneal/oral administration, to treat mice in order to the study the period as an anti-inflammatory model to prevent fibrosis induction;

for the preparation of glycolipids to study its effect on immune mediated colitis;

to coat the wells of microtiter plate and perform enzyme linked immunosorbent assay (ELISA).

Chemical Information

CAS Number	497155-61-0
Solubility (25°C)	Ethanol Methanol 10 mg/mL
Storage	-20°C

References

[1] Maya Margalit, et al. Am J Physiol Gastrointest Liver Physiol. Glucocerebroside treatment ameliorates ConA hepatitis by inhibition of NKT lymphocytes