GBA Human shRNA Plasmid Kit (Locus ID 2629)

Referência TR312830

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GBA Human shRNA Plasmid Kit (Locus ID 2629)

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SKU
TR312830
GBA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
 
Specifications
Product Data
Locus ID 2629
Synonyms GBA1; GCB; GLUC
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components GBA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2629). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000157, NM_001005741, NM_001005742, NM_001005749, NM_001005750, NM_001171811, NM_001171812, NM_001005741.1, NM_001005741.2, NM_001005742.1, NM_001005742.2, NM_000157.1, NM_000157.2, NM_000157.3, NM_001171811.1, NM_001171812.1, NM_001005749.1, NM_001005750.1, BC003356, BC003356.1, NM_001005741.3, NM_001005742.3, NM_001171812.2, NM_000157.4
UniProt ID P04062
Summary This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@quimigen.pt. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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