Ganglioside GM1 [37758-47-7]

Referência NB-64-43973-50mg

Tamanho : 50mg

Marca : Neo Biotech

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Ganglioside GM1

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Synonyms:

Catalog No. T82341 Copy Product Info
Ganglioside GM1 is one of the major sphingolipids (GSLs) on the cell surface of the central nervous system (CNS), which is protective of the CNS and is used in the study of neurological disorders.Ganglioside GM1 exerts protection against glutamate excitotoxicity through its oligosaccharides in wild-type and amyotrophic lateral sclerosis motor neurons.
Cas No. 37758-47-7
For research use only—not for human use. No sales to individuals. Use as intended only.
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Color:White
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Product Introduction

Bioactivity
Description
Ganglioside GM1 is one of the major sphingolipids (GSLs) on the cell surface of the central nervous system (CNS), which is protective of the CNS and is used in the study of neurological disorders.Ganglioside GM1 exerts protection against glutamate excitotoxicity through its oligosaccharides in wild-type and amyotrophic lateral sclerosis motor neurons.
Chemical Properties
Molecular Weight1546.841
FormulaC73H131N3O31
Cas No.37758-47-7
SmilesCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)\C=C\CCCCCCCCCCCCC
Storage & Solubility Information
StorageKeep away from direct sunlight,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Related Tags: Ganglioside GM1 chemical structure | Ganglioside GM1 formula | Ganglioside GM1 molecular weight