GABA A Receptor beta 3 (GABRB3) (NM_000814) Human Recombinant Protein

Referência TP762075

Tamanho : 50ug

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GABA A Receptor beta 3 (GABRB3) (NM_000814) Human Recombinant Protein

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SKU
TP762075
Purified recombinant protein of Human gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 1,Gln26-Tyr245, with N-terminal His tag, expressed in E. coli, 50ug
 
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Gln26-Tyr245) of GABRB3
Tag N-His
Predicted MW 25.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000805
Locus ID 2562
UniProt ID P28472
Cytogenetics 15q12
RefSeq Size 5811
RefSeq ORF 1419
Synonyms DEE43; ECA5; EIEE43
Summary This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. provided by RefSeq, Jul 2013
Protein Categories Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
SKU Description Size
LC400288 Lyophilized GABRB3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
LC411882 Lyophilized GABRB3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
LY400288 Transient overexpression lysate of gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 1 (as WB positive control) 100 ug
LY411882 Transient overexpression lysate of gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 2 (as WB positive control) 100 ug

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