FUNDC1 antibody - N-terminal region
Referência ARP53280_P050
Tamanho : 100ul
Marca : Aviva Systems Biology
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FUNDC1 Antibody - N-terminal region (ARP53280_P050)
| Datasheets/Manuals | Printable datasheet for anti-FUNDC1 (ARP53280_P050) antibody |
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| Publications | The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation |
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| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB, IP |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human FUNDC1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: MATRNPPPQDYESDDDSYEVLDLTEYARRHQWWNRVFGHSSGPMVEKYSV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-FUNDC1 (ARP53280_P050) antibody is Catalog # AAP53280 (Previous Catalog # AAPP30762) |
| Enhanced Validation | Relative Expression (Western Blot)  |
| Reference | Ross,M.T., (2005) Nature 434 (7031), 325-337 |
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| Gene Symbol | FUNDC1 |
| Gene Full Name | FUN14 domain containing 1 |
| Alias Symbols | MGC51029 |
| NCBI Gene Id | 139341 |
| Protein Name | FUN14 domain-containing protein 1 |
| Description of Target | FUNDC1 belongs to the FUN14 family. The exact function of FUNDC1 remains unknown. |
| Uniprot ID | Q8IVP5 |
| Protein Accession # | NP_776155 |
| Nucleotide Accession # | NM_173794 |
| Protein Size (# AA) | 155 |
| Molecular Weight | 17 kDa |
| Protein Interactions | SLC25A46; MAP1LC3A; MAP1LC3B; SENP2; SH3GLB1; MTERF3; GABARAPL1; GABARAPL2; YES1; TUFM; SNX1; EHHADH; CTBP2; CTBP1; UBC; |
