FNTA Antibody - C-terminal region - HRP
Referência ARP48521_T100-HRP
Tamanho : 100ul
Marca : Aviva Systems Biology
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Telefone : +1 850 650 7790
FNTA Antibody - C-terminal region : HRP (ARP48521_T100-HRP)
| Datasheets/Manuals | Printable datasheet for anti-FNTA (ARP48521_T100-HRP) antibody |
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| Predicted Species Reactivity | Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human FNTA |
| Predicted Homology Based on Immunogen Sequence | Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Pig: 92%; Rabbit: 100%; Rat: 92%; Sheep: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: DNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-FNTA (ARP48521_T100-HRP) antibody is Catalog # AAP48521 (Previous Catalog # AAPY01465) |
| Subunit | alpha |
| Reference | Veluthakal,R., (2007) Diabetes 56 (1), 204-210 |
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| Gene Symbol | FNTA |
| Gene Full Name | Farnesyltransferase, CAAX box, alpha |
| Alias Symbols | FPTA, PTAR2, PGGT1A |
| NCBI Gene Id | 2339 |
| Protein Name | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Description of Target | Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | A6NJW0 |
| Protein Accession # | NP_001018197 |
| Nucleotide Accession # | NM_001018677 |
| Protein Size (# AA) | 312 |
| Molecular Weight | 36kDa |
| Protein Interactions | UBC; HK2; DYRK1A; RPL13A; SAFB2; TGM2; STAT2; INHBB; VAV2; HDAC6; PTP4A3; GBP1; CENPF; TGFBR1; TGFB1; KRAS; HRAS; RHOB; FNTB; ACVR1; PTP4A2; |
