FITC-Dextran (MW 70000) [60842-46-8]

Biological Activity

FITC-Dextran (MW 70000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran (MW 70000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 70000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 70000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.

Product Citations

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  J Clin Periodontol. 2024 Feb 27.

  Gingipains may be one of the key virulence factors of Porphyromonas gingivalis to impair cognition and enhance blood–brain barrier permeability: An animal study
  FITC-Dextran (MW 70000) purchased from AbMole

Chemical Information

CAS Number	60842-46-8
Solubility (25°C)	Water 60 mg/mL
Storage	4°C, protect from light

References

[1] J P Draye, et al. Biomaterials. In vitro release characteristics of bioactive molecules from dextran dialdehyde cross-linked gelatin hydrogel films