Inquiry
Dispatch Time: About 3 working days
- Product Name
- FineTest®700 Anti-Human CD117/c-Kit Antibody(104D2)
- Catalogue No.
- F700-30047
- Form
- liquid
- Conjugation
- FineTest®700
- Conjugation Information
- FineTest® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
- Clonality
- Monoclonal
- Isotype
- IgG1, κ
- Clone ID
- 104D2
- Storage
- PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Alternative Names
- CD117|Kit|Mast/stem cell growth factor receptor Kit|Proto-oncogene c-Kit|SCFR|Tyrosine-protein kinase Kit|c-Kit antibody
- UniProt ID
- P10721
Application
- Tested Applications
- FC
- Recommended dilution
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Validated Images
Staining of the HEL cells with FineTest®700 Anti-Human CD117/c-Kit Antibody(104D2)(filled gray histogram) or FineTest®700 Mouse IgG1, κ Isotype Control(black histogram).Total viable cells were used for analysis. - Background
- CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.