EPOR Polyclonal Antibody, PE Conjugated
Referência bs-1424R-PE
Tamanho : 100uL
Marca : Bioss
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Telefone : +1 850 650 7790
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1424R-PE |
| Product Name | EPOR Polyclonal Antibody, PE Conjugated |
| Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Reactivity | Human, Rat |
| Predicted Reactivity | Mouse, Dog, Cow, Horse |
| Specifications | |
| Conjugation | PE |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human EPOR |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2057 |
| Swiss Prot | P19235 |
| Subcellular location | Secreted, Cell membrane, Extracellular matrix |
| Synonyms | EPO-R; Erythropoietin receptor; EPOR |
| Background | Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | |
| IF(IHC-F) | |
| IF(ICC) | |
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