EGTA [67-42-5]
Referência M9325-500mg
Tamanho : 500mg
Marca : AbMole Bioscience
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Telefone : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
Quality Control & Documentation
Biological Activity
EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+. EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages.
Product Citations
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Ann Hematol. 2022 Oct;101(10):2195-2208.
CD277 agonist enhances the immunogenicity of relapsed/refractory acute myeloid leukemia towards Vδ2 + T cell cytotoxicity
EGTA purchased from AbMole -
Cell Death Dis. 2021 Feb 15;12(2):179.
Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors
EGTA purchased from AbMole
Chemical Information
| Molecular Weight | 380.35 |
| Formula | C14H24N2O10 |
| CAS Number | 67-42-5 |
| Solubility (25°C) | Soluble in 0.1M NaOH |
| Storage | RT, dry, sealed |
References
[1] Laurel Oldach. Democratizing calcium visualization
[2] D Tripodi, et al. Demineralizing action of EGTA in endodontics
[3] D S Jong, et al. Sarcoplasmic reticulum calcium release in frog cut muscle fibers in the presence of a large concentration of EGTA
[4] N Stockbridge. EGTA