DL-Norepinephrine hydrochloride [55-27-6]
Referência NB-64-05236-100mg
Tamanho : 100mg
Marca : Neo Biotech
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DL-Norepinephrine hydrochloride (Synonyms: DL-lysine)
Catalog No. T13655 Copy Product Info
Purity: 98.82%
DL-Norepinephrine hydrochloride (DL-lysine) is a high-affinity basic amino acid substrate of amino acid transporter b0 + with a Km value in the range of 100-400 μM.
DL-Norepinephrine hydrochloride
Copy Product InfoSynonyms DL-lysine
DL-Norepinephrine hydrochloride (DL-lysine) is a high-affinity basic amino acid substrate of amino acid transporter b0 + with a Km value in the range of 100-400 μM.
Cas No. 55-27-6
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Purity:98.82%
Appearance:Solid
Color:White to Yellow
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Product Introduction
DL-Norepinephrine hydrochloride AI Summary
DL-Norepinephrine hydrochloride exhibits multifaceted bioactivity as an inhibitor across a range of biological targets and pathogens. In enzymatic assays, it inhibits the JMJD2A-Tudor Domain with a potency of 89125.1 nM, Rango-Importin beta complex formation at 125892.5 nM, HP1-beta Chromodomain interactions with methylated histone tails at 70794.6 nM, Polymerase Iota at 50118.7 nM and 47443.6 nM, Polymerase Eta at 56234.1 nM and 84921.4 nM, Polymerase Kappa at 79432.8 nM, and Marburg Virus entry into cells at 31622.8 nM. Moreover, it induces DNA re-replication in SW480 colon adenocarcinoma cells with a potency of 82.0 nM and inhibits GLP-1 Receptor Inverse Agonists at 10000.0 nM. Furthermore, it shows inhibitory activity in the development of antimalarial drugs targeting AMA1-RON with a potency of 17782.8 nM. In microbial assays, DL-Norepinephrine hydrochloride has marginal antifungal activity against Candida albicans ATCC 90028 (4.08%) and a potentially stimulatory or non-inhibitory effect on Cryptococcus neoformans H99 ATCC 208821 (-2.98%). Its antibacterial activities include inhibitions of 0.24% against Escherichia coli ATCC 25922, 15.27% against Klebsiella pneumoniae MDR ATCC 70063, 7.4% against Pseudomonas aeruginosa ATCC 27853, 28.77% against Acinetobacter baumannii ATCC 19606, and 10.44% against Staphylococcus aureus MRSA ATCC 43300. These findings suggest that DL-Norepinephrine hydrochloride holds significant potential as a versatile inhibitor with applications across various biological and antimicrobial domains..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | DL-Norepinephrine hydrochloride (DL-lysine) is a high-affinity basic amino acid substrate of amino acid transporter b0 + with a Km value in the range of 100-400 μM. |
| Synonyms | DL-lysine |
| Molecular Weight | 205.64 |
| Formula | C8H12ClNO3 |
| Cas No. | 55-27-6 |
| Smiles | Cl.NCC(O)c1ccc(O)c(O)c1 |
| Relative Density. | 1.397g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 240.00 mg/mL (1167.09 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1 mg/mL (4.86 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||
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