Dermatan Sulfate (Chondroitin Sulfate Type B Sodium Salt Porcine) [54328-33-5]

Where HexA is either Glucuronic acid or Iduronic Acid - in reality the vast majority of the Uronic Acids are Iduronic Acid based on the almost complete resistance of the DS to degradation by Chondroitinase AC On electrophoresis the DS gives a single band and separates clearly from standards of chondroitin sulfate and heparin. Dermatan Sulfate is a glycosaminoglycan molecule used in the synthesis of tissue engineering. Used in the synthesis of artificial cartilage as an applicable biomaterial.

Composition:
Disaccharide composition following depolymerisation by Chondroitinase ABC:
HexA-GalNAc,4S 88%
HexA-GalNAc,6S 5%
HexA,2S-GalNAc,4S 7%

Source:
Porcine Mucosa

Synonyms:
Chondroitin Sulfate B Sodium Salt; Chondroitin Sulfate Type B Sodium Salt; Dermatan Sulfate Sodium Salt

CAS No:
54328-33-5

Purity (HPLC):
≥50% after digestion

Method of Determining Identity:
≥90% 13C NMR Spectometric Analysis

Appearance:
White to off-white solid

Solubility (H2O):
As Reported

Melting Point:
>187°C (dec.)

Loss on Drying:
≤10 %

Total Nitrogen:
2.6 to 3.3 % (calcd.on dried substance)

Total Sulfur:
5.7 to 6.5 %(calcd.on dried substance)

Specific Rotation:
-68° (C=1,H2O)

Storage and Stability:
Lyophilized powder may be stored at RT. Stable for 12 months.