D-Glucose-13C6 [110187-42-3]

Referência HY-B0389A-250mg

Tamanho : 250mg

Marca : MedChemExpress

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Description

D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vivo

D-Glucose-13C6 (0.1 g in 25 g carrot medium for eggs or incorporated with 1 g of 99.5% sucrose in 15 mL water for adults) lightly decreases egg hatching rates, larval development, emerged adults, the period and the number of mating in Ceratitis capitata[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Ceratitis capitata [1]
Dosage: 0.1 g
Administration: Add into 25 g carrot medium for eggs or incorporated with 1 g of 99.5% sucrose in 15 mL water for adults
Result: Decreased hatching rate from 85% to 79% and number of emerged adults from 57% to 50.6%, prolonged development time.
Decreased the number and period of mating lightly for larvae labeled flies, while decreased the period of mating a bit more for adult labeled flies.
Masse moléculaire

186.11

Formule

13C6H12O6

CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=[13CH][13C@@H]([13C@H]([13C@@H]([13C@@H]([13CH2]O)O)O)O)O

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvant et solubilité
In Vitro: 

H2O : 100 mg/mL (537.32 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3732 mL 26.8658 mL 53.7317 mL
5 mM 1.0746 mL 5.3732 mL 10.7463 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (537.32 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureté et documentation
Références

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