D-Galactose [59-23-4]

Referência M9976-50g

Tamanho : 50g

Marca : AbMole Bioscience

Contactar o distribuidor local :


Telefone : +1 850 650 7790

All AbMole products are for research use only, cannot be used for human consumption.

D-Galactose Structure
Synonym:

D-(+)-Galactose


Quality Control & Documentation
Biological Activity

D-Galactose is a natural aldohexose and C-4 epimer of glucose, it accelerates the aging of invertebrates and mammals and is used as a model of aging. D-galactose given by oral route causes cognitive impairments in rats which are accompanied by oxidative damage. Cognitive impairments is observed in the open-field test in the 4th and 6th weeks after d-gal administration, as well as an impairment in spatial memory in the radial maze test after the 6th week of d-gal administration.

Chemical Information
Molecular Weight 180.16
Formula C6H12O6
CAS Number 59-23-4
Solubility (25°C) Water 100 mg/mL
Storage RT, dry, sealed
References

[1] Josiane Budni, et al. Behav Brain Res. Oral administration of d-galactose induces cognitive impairments and oxidative damage in rats

[2] Xu Cui, et al. J Neurosci Res. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid