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> Corn oil [8001-30-7]

Corn oil [8001-30-7]

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Referência HY-Y1888-50mL

Tamanho : 50mL

Marca : MedChemExpress

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Description

Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.

In Vivo

Corn oil-gavaged rats have 54% lower serum growth hormone (GH) levels, and replacement of GH into corn oil-gavaged rats by osmotic minipump infusion increase in situ MNCL cell proliferation to rates observed in water-gavaged animals[1].
Corn oil is commonly used as a feed additive or a delivery vehicle for lipophilic substances In an animal research setting[3].
Corn oil can become contaminated, and cause death/systemic infections several days after IP injections, so corn oil should be aliquoted and frozen (recommendation); thaw and make fresh solution each time.
Corn oil is more recommended for gavage administration[4].
Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female C57BL/6J mice (n = 90; age, 6 to 7 wk)[3]
Dosage: 0.1 mL.
Administration: Intraperitoneal injection every 48 h for a total of 4 injections over a 7-d period.
Result: At day 21, pharmaceutical-grade (PG) corn oil had a significantly higher pathology score compared with nonpharmaceutical-grade corn oil. No other significant differences between the corn oil groups were observed. The use of nonpharmaceutical grade corn oil did not result in adverse clinical consequences and is presumed safe to use for intraperitoneal injection in mice.
CAS No.
Appearance

Liquid (Density: 0.9195 g/cm3)

Color

Colorless to light yellow

SMILES

[Corn oil]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvant et solubilité
In Vitro: 

Ethanol : 10 mg/mL (Need ultrasonic)

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation
Références

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