Chondroitin sulfate [9007-28-7]
Referência M10320-1g
Tamanho : 1g
Marca : AbMole Bioscience
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Chondroitin polysulfate; Chonsurid
Quality Control & Documentation
Biological Activity
Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. Chondroitin sulfate (200 mg/mL) decreases the chondrocyte susceptibility to single nucleotide polymorphism-induced apoptosis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS, MMPs.
Product Citations
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Int J Biol Macromol. 2025 Sep 5;327(Pt 2):147486.
Cathepsin K and glycosaminoglycans differentially regulate matrix metalloproteinase activity in dentin under various pH conditions
Chondroitin sulfate purchased from AbMole
Chemical Information
| Formula | (C14H21NO14S)n |
| CAS Number | 9007-28-7 |
| Solubility (25°C) | Water ≥ 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
References
[1] Johanne Martel-Pelletier, et al. Molecules. Discrepancies in composition and biological effects of different formulations of chondroitin sulfate
[2] Tadahisa Mikami, et al. Biochim Biophys Acta. Biosynthesis and function of chondroitin sulfate
[3] Giuseppe M Campo, et al. J Cell Biochem. Glycosaminoglycans modulate inflammation and apoptosis in LPS-treated chondrocytes
[4] J Monfort, et al. Ann Rheum Dis. Biochemical basis of the effect of chondroitin sulphate on osteoarthritis articular tissues