CHAC1 Polyclonal Antibody, PE-Cy7 Conjugated
Referência bs-6795R-PE-Cy7-20uL
Tamanho : 20uL
Marca : Bioss
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Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-6795R-PE-Cy7 |
| Product Name | CHAC1 Polyclonal Antibody, PE-Cy7 Conjugated |
| Applications | WB, FCM |
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human, Dog, Cow, Pig, Rabbit |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human CHAC1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 79094 |
| Swiss Prot | Q9BUX1 |
| Subcellular location | Cytoplasm |
| Synonyms | Cation transport regulator-like protein 1; Blocks Notch protein; Botch; CHAC1 |
| Background | Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |