CDK5 Antibody - N-terminal region - Biotin
Referência ARP38525_T100-Biotin
Tamanho : 100ul
Marca : Aviva Systems Biology
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CDK5 Antibody - N-terminal region : Biotin (ARP38525_T100-Biotin)
| Datasheets/Manuals | Printable datasheet for anti-CDK5 (ARP38525_T100-Biotin) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | Biotin |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human CDK5 |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALR |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-CDK5 (ARP38525_T100-Biotin) antibody is Catalog # AAP38525 (Previous Catalog # AAPP20716) |
| Reference | Otyepka,M., et al., (2006) J. Biol. Chem. 281 (11), 7271-7281 |
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| Gene Symbol | CDK5 |
| Gene Full Name | Cyclin-dependent kinase 5 |
| Alias Symbols | LIS7, PSSALRE |
| NCBI Gene Id | 1020 |
| Protein Name | Cyclin-dependent kinase 5 |
| Description of Target | CDK5 is probably involved in the control of the cell cycle. CDK5 can interact with d1 and d3-type G1 cyclins and phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. CDK5 can also interacts with p35 which activates the kinase |
| Uniprot ID | Q00535 |
| Protein Accession # | NP_004926 |
| Nucleotide Accession # | NM_004935 |
| Protein Size (# AA) | 292 |
| Molecular Weight | 33kDa |
| Protein Interactions | CHFR; CCND2; CDKN1A; EGFR; UBC; DCLK3; CDK5; CCNE1; CDK5R1; CABLES1; CABLES2; STIP1; CDKN1B; CCND3; CCNB1; C2CD5; KIAA0195; FIBP; PPARG; CDK18; HSP90AB1; HSP90AA1; HIST1H1B; GLUD1; CDK3; CDC25B; CCT6A; CCNA2; CCT3; TCP1; CCT5; CDC37; CCT8; CCT2; CCT4; CCT |
