Cd24a rat monoclonal antibody, clone 91, Low Endotoxin
Size:
500 ug
Conjugation:
Unconjugated
View other "Cd24 or NP_033976.1" antibodies
Specifications
Product Data
Clone Name
91
Application
FC
Recommended Dilution
Flow Cytometry. (Ref.8) Immunohistochemistry on Frozen Sections. (Ref.8) Immunoprecipitation. (Ref.8) Clone 91 can be used to inhibit B-cell differentiation. (Ref.8)
Reactivity
Mouse
Antibody Host
Rat
Isotype
IgG2a
Clonality
Monoclonal
Specificity
This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3)
Synonyms
X62 heat stable antigen, HSA
Reference Data
Protein Categories
ADC Targets, CD Markers, Chemokines, Cytokines, Growth Factors, Intracellular Proteins
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
