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> CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)

CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)

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Referência NB-64-51511-1mg

Tamanho : 1mg

Marca : Neo Biotech

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CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)

(Synonyms: Proml1, Prominin-like protein 1, Prominin-1, Prom1, Prom, CD133, Antigen AC133 homolog) Copy Product Info

Synonyms: Proml1, Prominin-like protein 1, Prominin-1, Prom1, Prom, CD133, Antigen AC133 homolog

Catalog No. TMPH-02842 Copy Product Info
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Other Forms of CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO):
CD133/PROM1 Protein, Rat, Recombinant (mFc)
CD133/PROM1 Protein, Rat, Recombinant (His)
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Species
Mouse
Expression System
E. coli
TagN-6XHis-SUMO
Accession NumberO54990
Amino AcidGANVEKLLCEPYENKKLLQVLDTPYLLKEQWQFYLSGMLFNNPDINMTFEQVYRDCKRGRGIYAAFQLENVVNVSDHFNIDQISENINTELENLNVNIDSIELLDNTGRKSLEDFAHSGIDTIDYSTYLKETEKSPTEVNLLTFASTLEAKANQLPEGKPKQAFLLDVQNIRAIHQHLLPPVQQSLNTLRQSVWTLQQTSNKLPEKVKKILASLDSVQHFLTNNVSLIVIGETKKFGKTILGYFEHYLHWVFYAITEKMTSCKPMATAMDSAVNGILCGYVADPLN
Construction509-794 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsProml1, Prominin-like protein 1, Prominin-1, Prom1, Prom, CD133, Antigen AC133 homolog
Research Background
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Chemical Properties
Molecular Weight48.5 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Proml 1Prominin1Prom 1CD 133
Related Tags: CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO) chemical structure | CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO) molecular weight