General Information
| Short Description | Rabbit polyclonal antibody anti-PP2A-alpha (410-486) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Monkey/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.5-1.5 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthetic peptide taken within amino acid region 410-486 on human Serine/Threonine-Protein Phosphatase 2A, B56-Alpha subunit. |
| Immunogen Region | 410-486 |
Additional Info
| Tissue Specificity | Widely expressed with the highest expression in heart and skeletal muscle. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha IsoformPp2a B Subunit Isoform B'-AlphaPp2a B Subunit Isoform B56-AlphaPp2a B Subunit Isoform Pr61-AlphaPr61alphaPp2a B Subunit Isoform R5-Alpha |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusChromosomeCentromereFrom Mitotic Prophase To MetaphaseLocalizes At The Inner Centromere Between A Pair Of Sister KinetochoresDecreased Expression At The Onset Of Anaphase |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha Isoform antibodyAnti-Pp2a B Subunit Isoform B'-Alpha antibodyAnti-Pp2a B Subunit Isoform B56-Alpha antibodyAnti-Pp2a B Subunit Isoform Pr61-Alpha antibodyAnti-Pr61alpha antibodyAnti-Pp2a B Subunit Isoform R5-Alpha antibodyAnti-PPP2R5A antibody |
Information sourced from Uniprot.org