Anti-Human CD14 [Clone UCHM-1] - Biotin
Referência C154-50
Tamanho : 50ug
Marca : Leinco Technologies
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AntiHuman CD14 [Clone UCHM1] — Biotin
AntiHuman CD14 [Clone UCHM1] — Biotin
Product No.: C154
Clone UCHM1 Target CD14 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names P35 Isotype IgG2a Applications FC |
Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This biotinylated antibody is stable when stored at 28°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828609 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this UCHM1 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone UCHM1 recognizes an epitope on human CD14. Background CD14 is a 5355 kD GPIanchored single chain glycoprotein that plays a role in the clearance of gramnegative pathogens by interacting with other proteins, including TLR4 and MD2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a highaffinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils. Antigen Distribution CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes. Ligand/Receptor LPS PubMed NCBI Gene Bank ID UniProt.org Research Area Cell Biology . Immunology . Neuroinflammation . Neuroscience References & Citations1. Freyssinet, JM et al. (1997) J Clin Invest. 99(7): 1546–1554. PubMed 2. Ulrich, Costabel et al. (1995) CHEST 108: 1614 3. Ulevitch, RJ et al. (1993) Immunobiology 187: 227 4. Schumann, RR et al. (1994) Medical Microbiol Immunol. 183: 279 5. Verhasselt, V et al. (1997) J Immunol. 158: 2919 6. Kirkland, TN et al. (2000) J Biol Chem. 275: 3144 Você também pode estar interessado nos seguintes produtos:
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