Anti-Endophilin-A1/SH3GL2, Biotinylated antibody (Internal) {Biotin}

Referência NB-22-33069-100

Tamanho : 100ug

Marca : Neo Biotech

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General Information

Short DescriptionGoat polyclonal antibody anti-Endophilin-A1/SH3GL2, Biotinylated (Internal) is suitable for use in ELISA and Western Blot research applications.
ApplicationsPep-ELISA/WB
HostGoat
ReactivityHuman/Pig
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationBiotin
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:64000.
WB: Approx 38kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 40.0kDa according to NP_003017.1). Recommended concentration: 0.3-1µg/ml. See non-biotinylated pare
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene Symbol
Gene ID
Uniprot ID
Accession NumberNP_003017.1
Immunogen RegionInternal
Immunogen SequenceCSLEFPTGDSTQPN.

Additional Info

Function Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
Protein Name Endophilin-A1
Een-B1
Endophilin-1
Sh3 Domain Protein 2a
Sh3 Domain-Containing Grb2-Like Protein 2
Database Links








Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Early Endosome
Presynapse
Alternative Antibody Names Anti-Endophilin-A1 antibody
Anti-Een-B1 antibody
Anti-Endophilin-1 antibody
Anti-Sh3 Domain Protein 2a antibody
Anti-Sh3 Domain-Containing Grb2-Like Protein 2 antibody
Anti-SH3GL2 antibody
Anti-CNSA2 antibody
Anti-SH3D2A antibody

Information sourced from Uniprot.org

Citations

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