| Short Description : | Rat monoclonal anti-Epithelial cell adhesion molecule for use in FC in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC |
| Host: | Rat |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | G8.8 |
| Isotype: | IgG2ak |
| Conjugation: | APC |
| Concentration: | 5 Mu L/Test |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction: | Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
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| Post Translational Modifications | Glycosylation at Asn-198 is crucial for protein stability. |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Protein Name | Epithelial Cell Adhesion MoleculeEp-CamEpithelial Glycoprotein 314Egp314Megp314Protein 289aTumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
| Database Links | |
| Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
| Alternative Antibody Names | Anti-Epithelial Cell Adhesion Molecule antibodyAnti-Ep-Cam antibodyAnti-Epithelial Glycoprotein 314 antibodyAnti-Egp314 antibodyAnti-Megp314 antibodyAnti-Protein 289a antibodyAnti-Tumor-Associated Calcium Signal Transducer 1 antibodyAnti-Cd Antigen Cd326 antibodyAnti-Epcam antibodyAnti-Tacstd1 antibody |
Information sourced from Uniprot.org