| Short Description : | Mouse monoclonal anti-CD2 for use in FC, WB, IF and IHC in Cat and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC/WB/IF/IHC |
| Host: | Mouse |
| Reactivity: | Cat/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | EBS-CD-002 |
| Isotype: | IgG2ak |
| Conjugation: | Unconjugated |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification: | Affinity purified from tissue culture. |
| Dilution Range: | Flow cytometry (0.5-1.0 µg/million cells in 0.1 ml). Immunoblotting (1.0-2.0 µg/ml). Immunofluorescence (0.5-1.0 µg/ml). Immunohistology (1.0-2.0 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues h |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
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| Gene ID: | |
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| Immunogen: | A BALB/c mouse was immunized with human Sézary T cells. Fusion partner: NS-1. |
| Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Protein Name | T-Cell Surface Antigen Cd2Erythrocyte ReceptorLfa-2Lfa-3 ReceptorRosette ReceptorT-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Antigen Cd2 antibodyAnti-Erythrocyte Receptor antibodyAnti-Lfa-2 antibodyAnti-Lfa-3 Receptor antibodyAnti-Rosette Receptor antibodyAnti-T-Cell Surface Antigen T11/Leu-5 antibodyAnti-Cd Antigen Cd2 antibodyAnti-CD2 antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org