Adipokinetic hormone (Gryllus bimaculatus) [113800-65-0]

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Referência NB-64-86412-50mg

Tamanho : 50mg

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Adipokinetic hormone (Gryllus bimaculatus)

(Synonyms: Grybi-AKH) Copy Product Info

Synonyms: Grybi-AKH

Catalog No. T83166 Copy Product Info

Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH), an adipokinetic hormone, mobilizes lipids and carbohydrates from the insect fat body, regulating energy homeostasis. It also enhances the locomotor activity of the two-spotted cricket and has potential applications in human medical studies for body weight regulation, weight loss induction, and alleviation of glycogen storage disorders [1] [2] [3].

Cas No. 113800-65-0

For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity

Description	Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH), an adipokinetic hormone, mobilizes lipids and carbohydrates from the insect fat body, regulating energy homeostasis. It also enhances the locomotor activity of the two-spotted cricket and has potential applications in human medical studies for body weight regulation, weight loss induction, and alleviation of glycogen storage disorders [1] [2] [3].
In vivo	Adipokinetic hormone from Gryllus bimaculatus (100 pmol/per; topical application; single) enhances locomotive behavior by elevating haemolymph lipid levels [1].
Synonyms	Grybi-AKH

Chemical Properties

Molecular Weight	919.98
Formula	C₄₃H₅₇N₁₁O₁₂
Cas No.	113800-65-0
Smiles	C([C@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(=O)[C@@H]2CCC(=O)N2)[C@@H](C)C)=O)CC(N)=O)=O)=O)CO)=O)[C@@H](C)O)=O)=O)C(N)=O)C=3C=4C(NC3)=CC=CC4
Sequence	H-Pyr-Val-Asn-Phe-Ser-Thr-Gly-Trp-NH₂
Sequence Short	XVNFSTGW

Storage & Solubility Information

Storage	Keep away from moisture Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Related Tags: Adipokinetic hormone (Gryllus bimaculatus) chemical structure | Adipokinetic hormone (Gryllus bimaculatus) in vivo | Adipokinetic hormone (Gryllus bimaculatus) formula | Adipokinetic hormone (Gryllus bimaculatus) molecular weight