Tamanho : 10mg
Telefone : +1 850 650 7790
Synonyms:
| Description | 8-Azakinetin riboside, a structural analog of kinetin riboside, exhibits cytotoxic activity [1]. |
| In vitro | Azakinetin riboside (compound 7) demonstrates cytotoxic activity against HeLaWT, MCF7, Caco-2, OVCAR-3, MIAPaCa-2, and MRC-5 cells at concentrations ranging from 0-100 µM over 24, 48, and 72 hours. The IC50 values are more than 100, 27, 25, more than 100, more than 100, 100 µM at 24 hours; 14.5, 4.3, 18.7, 76, 2.8, 11.7 µM at 48 hours; and 4.6, 3.8, 11.5, 1.1, 1.1, 4.6 µM at 72 hours, respectively. |
| Molecular Weight | 348.31 |
| Formula | C14H16N6O5 |
| Cas No. | 2347524-00-7 |
| Smiles | O[C@H]1[C@H](N2C=3C(N=N2)=C(NCC4=CC=CO4)N=CN3)O[C@H](CO)[C@H]1O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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