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2-Phenylethanol [60-12-8]

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Referência NB-64-00147-10g

Tamanho : 10g

Contactar o distribuidor local :

Telefone : +1 850 650 7790

Marca : Neo Biotech

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Contactar o distribuidor local :

Telefone : +1 850 650 7790

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2-Phenylethanol

(Synonyms: Phenylethanol, Phenethyl alcohol, Benzyl carbinol, Benzeneethanol, 2-Phenylethyl alcohol) Copy Product Info

Synonyms: Phenylethanol, Phenethyl alcohol, Benzyl carbinol, Benzeneethanol, 2-Phenylethyl alcohol

Catalog No. T0011 Copy Product Info

Purity: 97.34%

2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.

Cas No. 60-12-8

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97.34%

Appearance:Liquid

Color:Transparent

Product Introduction

2-Phenylethanol AI Summary

2-Phenylethanol exhibits a range of biological activities relevant to various applications. It demonstrates binding affinity to beta cyclodextrin with a log Ks value of 2.15. It has shown bioactivities related to the inhibition of enzymes such as Tyrosyl-DNA Phosphodiesterase (TDP1) and Human Apurinic/apyrimidinic Endonuclease 1 (APE1), and it is potent in inducing DNA re-replication in SW480 colon adenocarcinoma cells. This compound has also been tested for blocking the entry of the Ebola virus, showing potency in the low nanomolar to low micromolar range. In agricultural contexts, 2-Phenylethanol shows thrips luring activity against various species, including female Thrips tabaci, male New Zealand Thrips obscuratus, and female New Zealand Thrips obscuratus, with ratios of 3.8, 9.5, and 9.8, respectively. It also exhibits antifungal activity against Colletotrichum camelliae with significant mycelial growth inhibition at different concentrations, achieving up to 92.6% inhibition. The compound displays fungitoxicity against Colletotrichum gloeosporioides and fungicidal activity against Athelia rolfsii and Pythium sp. Additionally, it has shown bioactively both in growth inhibition and germination inhibition in Triticum aestivum (wheat) seeds. Regarding antiviral activities, 2-Phenylethanol has shown some efficacy against SARS-CoV-2 by inhibiting virus-induced cytotoxicity in VERO-6 cells, although with relatively weak potency as indicated by IC50 values greater than 20,000 nM. It also displays bioactivity in inhibiting tyrosinase with an IC50 of 315.0 ug/mL and antibacterial activity against Fusobacterium nucleatum with an MIC of 8.0 ug/mL..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
Synonyms	Phenylethanol, Phenethyl alcohol, Benzyl carbinol, Benzeneethanol, 2-Phenylethyl alcohol

Chemical Properties

Molecular Weight	122.16
Formula	C₈H₁₀O
Cas No.	60-12-8
Smiles	OCCC1=CC=CC=C1
Relative Density.	>= 1.019 - <= 1.022 g/cm3. Temperature:20 °C.;>= 1.017 - <= 1.02 g/cm3. Temperature:25 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20 mg/mL (163.72 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	8.1860 mL	40.9299 mL	81.8599 mL	409.2993 mL
5 mM	1.6372 mL	8.1860 mL	16.3720 mL	81.8599 mL
10 mM	0.8186 mL	4.0930 mL	8.1860 mL	40.9299 mL
20 mM	0.4093 mL	2.0465 mL	4.0930 mL	20.4650 mL
50 mM	0.1637 mL	0.8186 mL	1.6372 mL	8.1860 mL
100 mM	0.0819 mL	0.4093 mL	0.8186 mL	4.0930 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

VirusProteaseVirus ProteasePhenylethyl alcoholInhibitorinhibitBacterialAntibiotic2-Phenylethanol2Phenylethanol2 Phenylethanol

Related Tags: 2-Phenylethanol chemical structure | 2-Phenylethanol formula | 2-Phenylethanol molecular weight